2. Cardiovascular Disease

Cardiovascular Disease

Cardiovascular Disease

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Cardiovascular diseases (CVDs) are the leading causes of death and disability worldwide. CVDs include diseases of the heart, vascular diseases of the brain and diseases of blood vessels. Caused by atherosclerosis, coronary heart disease and cerebrovascular disease are the most common forms of CVDs. Other less common forms of CVDs include rheumatic heart disease and congenital heart disease. A large percentage of CVDs is preventable through the reduction of behavioral risk factors such as tobacco use, physical inactivity and unhealthy diet. Dietary sodium reduction can alleviate the long-term risk of cardiovascular disease events. Statin therapy is an effective intervention in both the primary and secondary preventions of CVDs in those who are at high risk.

Cat. No. Product Name CAS No. Purity Chemical Structure
  • HY-N3125
    Osajin 482-53-1 98.18%
    Osajin is the major bioactive isoflavone present in the fruit of Maclura pomifera with antitumor, antioxidant and anti-inflammatory activities.
    Osajin
  • HY-N3670
    Cycloolivil 3064-05-9 98.54%
    Cycloolivil (Isoolivil) is a natural polyphenolic compound with a significant radical scavenging activity. Antioxidant and Antiaggregant effects.
    Cycloolivil
  • HY-N4305
    Notoginsenoside FP2 1004988-75-3 99.61%
    Notoginsenoside FP2, a dammarane-Type Bisdesmoside isolated from the Fruit Pedicels of Panax notoginseng, has potential to treat cardiovascular disease.
    Notoginsenoside FP2
  • HY-N6243
    Veratrosine 475-00-3 99.0%
    Veratramine is a steroidal alkaloid extracted from the roots and rhizomes of Veratrum californicum.
    Veratrosine
  • HY-N8102
    Echinocystic acid 28-O-β-D-glucoside 99633-30-4 99.11%
    Echinocystic acid 28-O-β-D-glucoside is a metabolite of Echinocystic acid by microbial oxidation and glucosidation. Echinocystic acid 28-O-β-D-glucoside is a tissue factor pathway inhibitor, with an IC50 of 10.61 nM.
    Echinocystic acid 28-O-β-D-glucoside
  • HY-N9526
    Lyciumin B 125756-66-3 99.0%
    Lyciumin B is a cyclic peptide isolated from Lysium chinense.
    Lyciumin B
  • HY-P1095
    Ivachtin 745046-84-8 ≥99.0%
    Ivachtin (Caspase-3 Inhibitor VII; compound 7a) is a nonpeptide, noncompetitive and reversibl caspase-3 inhibitor with an IC50 of 23 nM. Ivachtin has modest selectivity for the remaining caspases.
    Ivachtin
  • HY-P1185
    Antagonist G 115150-59-9 99.05%
    Antagonist G is a potent vasopressin antagonist. Antagonist G is also a weak antagonist of GRP and Bradykinin. Antagonist G induces AP-1 transcription and sensitizes cells to chemotherapy.
    Antagonist G
  • HY-P1197
    Kisspeptin-10 (mouse, rat) 478507-53-8 99.53%
    Kisspeptin-10 (mouse, rat) is a potent vasoconstrictor and inhibitor of angiogenesis. Kisspeptin-10 (mouse, rat) is a ligand for the rodent kisspeptin receptor (KISS1, GPR54). Kisspeptin-10 reduces Methotrexate-induced reproductive toxicity as a potential antioxidant compound.
    Kisspeptin-10 (mouse, rat)
  • HY-P1457
    Adrenomedullin (AM) (13-52), human 154765-05-6 99.16%
    Adrenomedullin (AM) (13-52), human is a 40 amino acid peptide, which acts as an endothelium-dependent vasodilator agent.
    Adrenomedullin (AM) (13-52), human
  • HY-P1741
    Fibrinogen-Binding Peptide 137235-80-4 99.83%
    Fibrinogen-Binding Peptide (designed by anticomplementarity hypothesis) is a presumptive peptide mimic of the vitronectin binding site on the fibrinogen receptor. Fibrinogen-Binding Peptide binds fibrinogen and inhibits both the adhesion of platelets to fibrinogen and platelet aggregation, and also inhibits the adhesion of platelets to vitronectin.
    Fibrinogen-Binding Peptide
  • HY-P1921
    YRGDS Fibronectin Fragment 134282-68-1 98.86%
    YRGDS Fibronectin Fragment is a fibronectin fragment, an adhesion peptide that displays strong binding affinity to thrombin-stimulated platelets.
    YRGDS Fibronectin Fragment
  • HY-P3068
    ACTH (1-16) (human) 5576-42-1 99.95%
    ACTH (1-16) (human) (Adrenocorticotropic hormone (1-16)) is an ACTH fragment. ACTH (1-16) (human) improves cardiovascular function and survival in experimental hemorrhagic shock.
    ACTH (1-16) (human)
  • HY-P3138
    (Sar1)-Angiotensin II 51833-69-3 99.84%
    (Sar1)-Angiotensin II, an analogue of Angiotensin II, is a specific agonist of angiotensin AT1 receptor. (Sar1)-Angiotensin II binds to brain membrane-rich particles, with a Kd of 2.7 nM. (Sar1)-Angiotensin II can stimulate protein synthesis and cell growth in embryonic chick myocytes.
    (Sar1)-Angiotensin II
  • HY-P3557
    Mibenratide 1239011-83-6 99.77%
    Mibenratide, a small cyclic peptide, is an adrenergic β1 receptor antagonist. Mibenratide can be used for heart failure research.
    Mibenratide
  • HY-P3910
    [Val4] Angiotensin III 100900-28-5 98.51%
    [Val4] Angiotensin III is an angiotension III peptide. [Val4] Angiotensin III is a potent full agonist of Gαq and βarr2 response, with pEC50 values of 8.31 and 8.44, respectively.
    [Val4] Angiotensin III
  • HY-P4560
    H-Pro-Phe-OH 13589-02-1 99.14%
    H-Pro-Phe-OH is a dipeptide containing proline and phenylalanine, which can serve as a substrate for prolinase. H-Pro-Phe-OH can also be used for polypeptide synthesis, where phenylalanine is an aromatic amino acid that can inhibit the activity of Angiotensin-converting enzyme (ACE, HY-P2983).
    H-Pro-Phe-OH
  • HY-P4682
    Neuromedin U-25 (porcine) 98395-76-7 98.03%
    Neuromedin U-25 (porcine) is a uterus stimulating and hypertensive peptides.
    Neuromedin U-25 (porcine)
  • HY-100418
    SKA-111 1369170-24-0 99.97%
    SKA-111 is a selective activator of potassium phannel KCa 3.1 , evokes KCa 3.1 membrane hyperpolarization in porcine endothelial cell. SKA-111 is capable of improving Bradykinin (HY-P0206)-induced coronary dilations in the isolated rat heart and can be used for cardiovascular disease research.
    SKA-111
  • HY-100635
    Diacetolol 22568-64-5
    Diacetolol is an active metabolite of the beta-adrenoceptor blocking agent Acebutolol (HY-17497).
    Diacetolol
Cat. No. Product Name / Synonyms Application Reactivity